Flexible Polycaprolactone and Polycaprolactone/Graphene Scaffolds for Tissue Engineering

Fuzzy VIKOR Optimization for Designing High Performance Hydroxyapatite/Polycaprolactone Scaffolds for Hard Tissue Engineering

Polycaprolactone Scaffolds Fabricated via Bioextrusion for Tissue Engineering Applications

The most promising approach in Tissue Engineering involves the seeding of porous, biocompatible/biodegradable scaffolds, with donor cells to promote tissue regeneration. Additive biomanufacturing processes are increasingly recognized as ideal techniques to produce 3D structures with optimal pore size and spatial distribution, providing an adequate mechanical support for tissue regeneration whil...

Aligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering

Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...

Tissue Engineering Scaffolds: History, Types and Construction Methods

Tissue engineering is a rapidly growing research field, potentially capable of de novo tissue and organ construction. This approach is used to improve efficiency both in the tissue and cell culture. This method is required to provide bodies in vivo three-dimensional conditions outside of the body (ex vivo). To achieve this goal, given tissue cells are cultured on the tissue engineering scaffold...

Evaluation of Polyethylene Glycol Diacrylate-Polycaprolactone Scaffolds for Tissue Engineering Applications

Polyethylene Glycol Diacrylate (PEGDA) tissue scaffolds having a thickness higher than 1 mm and without the presence of nutrient conduit networks were shown to have limited applications in tissue engineering due to the inability of cells to adhere and migrate within the scaffold. The PEGDA scaffold has been coated with polycaprolactone (PCL) electrospun nanofiber (ENF) membrane on both sides to...